يعرف هذا الاختبار عالميا بعدة اسماء منها :
Hemoglobin A1c, HbA1c, Glycohemoglobin, Glycated hemoglobin, Glycosylated hemoglobin
Also known as:
Hemoglobin A1c, HbA1c, Glycohemoglobin, Glycated hemoglobin, Glycosylated hemoglobin
*الاسم الرسمي له : A1c
Formal name: A1c
*لماذا نقوم بهذا الاختبار؟
لمراقبة مرض السكري وايضا للمساعده في قرارات علاجه.
Why get tested?
To monitor a person’s diabetes and to aid in treatment decisions
*متى يطلب الطبيب عمل هذا الاختبار؟
عندما يشخص السكري لاكثر من 2 الى اربع مرات بالسنه.
When to get tested?
When first diagnosed with diabetes and then 2 to 4 times per year
When is it ordered?
Depending on the type of diabetes that you have, how well your diabetes is controlled, and your doctor, your A1c may be measured 2 to 4 times each year
.
The American Diabetes Association (ADA) recommends testing your A1c:
4 times each year if you have type 1 or type 2 diabetes and use insulin; or
2 times each year if you have type 2 diabetes and do not use insulin.
When someone is first diagnosed with diabetes or if control is not good, A1c may be ordered more frequently.
*العينه التي نجري عليها الاختبار:
عينة دم عن طريق الوريد او عن طريق شكة بالاصبع
Sample required?
A blood sample is obtained by inserting a needle into a vein in the arm or a drop of blood is taken from your
finger by pricking it with a small, pointed lancet.
*طبيعة عمل الاختبار:
A1c يقيم القيمة المتوسطه للجلوكوز في الدم للاشهر 2 او 3 الاخيــره
حيث الـHBA <هيموجلوبين A > يحمل الاكسجين داخل خلايا الدم الحمراء
وعندما يرتبط الهيموجلوبين A مع الجلوكوز
يبقى هنا لحياة الخلايا الحمراء< 120يوم>
زيادة الجلوكوز في الدم
يصاحبها زيادة للارتباط بالهيموجلوبين A
هذا المزيج والمركب المكون من الهيموجلوبين A والجلوكوز في الدم يسمى A1c أو glycohemoglobin
What is being tested?
The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycosylated hemoglobin.
As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A (the primary form of hemoglobin in adults). Hemoglobin is a red protein that carries oxygen in the red blood cells (RBCs)).
Once the glucose is bound to the hemoglobin A, it remains there for the life of the red blood cell (about 120 days). The more glucose that is in the blood, the more that binds to hemoglobin A.
This combination of glucose and hemoglobin A is called A1c (or hemoglobin A1c or glycohemoglobin). A1c levels do not change quickly but will shift as older RBCs die and younger ones take their place.