abu yazan مراقب عام
عدد المساهمات : 125 العمر : 51 تاريخ التسجيل : 27/11/2008
| موضوع: بعض اسباب الانيميا الجمعة 5 ديسمبر - 5:20 | |
| ANAEMIA The first step in the diagnosis is to carry out a complete blood count (CBC), blood indices (mean corpuscular volume MCV & mean corpuscular hemoglobin MCH) as well as a reticulocytic count. NORMOCYTIC NORMOCHROMIC ANAEMIA (normal MCV & MCH):
1) Anaemia of chronic disorders :
• Chronic infections : Culture, ESR, CRP. • Chronic inflammations : Rheumatoid factor, Autoantibodies (ANA, DNA, etc.). • Hematologic malignancy : Bone marrow, Immunophenotyping, Cytochemistry. • Solid tumours : Tumour markers.
2) Some hemolytic anaemias . 3) Hypothyroidism : Free (T3 & T4), TSH. 4) Renal failure : Creatinine clearance . 5) Addison's disease : Cortisol (9 a.m. & 9 p.m.), ACTH. 6) Panhypopituitarism : FSH, LH, PRL, TSH, ACTH, Growth hormone.
MICROCYTIC HYPOCHROMIC ANAEMIA (Decreased MCV & MCH ):
1) Iron deficiancy : Serum Iron , TIBC , Ferritin.
2) Thalassaemia & Sickle cell anaemia : Hemoglobin electrophoresis, PCR.
MACROCYTIC ANAEMIA (Increased MCV):
Vitamin B12 , Folate , Liver functions, Bone marrow iron stain for refractory or Siderblastic anaemia. HEMOLYTIC ANAEMIA :
• Indirect Bilirubin is increased. • Haptoglobin is consumed. • Hemoglobin electrophoresis to detect any hemoglobinopathy such as Thalassaemia or Sickle cell anaemia. • Quantitative G6PD assay. • Coomb's test ( indirect & direct for both cold and warm antibodies) to diagnose Immune hemolytic anaemia. • Acidified Serum Lysis Test for paroxysmal nocturnal haemoglobinuria. • Red cell Pyruvate Kinase assay. • Hemoglobin H detection. [right] | |
|
hemato عضو فضي
عدد المساهمات : 546 تاريخ التسجيل : 13/08/2008
| موضوع: رد: بعض اسباب الانيميا الأحد 8 مارس - 23:33 | |
| | |
|
amany farag عضو ذهبي
عدد المساهمات : 635 العمر : 57 تاريخ التسجيل : 07/06/2009
| موضوع: رد: بعض اسباب الانيميا الأحد 14 نوفمبر - 12:44 | |
| | |
|