TIBC
Definition :
TIBC is a blood test that shows if there is too much or too little iron in the blood this test helps measure the ability of a protein called transferrrin to carry the iron in the blood.
Why the test is performed ?
When the health care provider suspect low iron ( deficiency) as accuses of anaemia.
About 65% of the iron in the body is carried in a part of red blood cells called hemoglobin .
Another part of iron is carried in a pat of muscle tissue called myoglobin .
About 30 % of iron in the body is stored as a substance called ferritin in the liver , spleen , bone marrow. A small amount of the body's iron moves through the body in the blood stream as a part of a protein called transferrin .
As iron test measure the amount of iron in transferrin , each transferrin molecule can carry two iron atoms, Normally about 30% of the free ( spaces) for iron in tranferrinare filled , By filling up all the available spaces , TIBC is higher than normal
When the body's iron stores are low.
Normal values
Iron = 60-170 micro gram/ dl
TIBC = 240-450 micro gram/dl
Transferrin saturation= 20-50 %
? What abnormal results mean
Higher than normal may mean iron deficiency anaemia.
Lower than normal may mean inflammation ,
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